Ginger in fatty liver disease with type 2 diabetes: what a clinical trial shows
Dott. Armando Colonnese; Last updated: October 2026
In brief: A clinical study evaluated whether three months of ginger capsules could modify metabolic and liver parameters in people with type 2 diabetes and non-alcoholic fatty liver disease. Some metabolic changes emerged, but there was no documented improvement in the amount of fat in the liver.The authors' summary describes a randomized, double-blind, placebo-controlled study. Randomization assigns participants to groups by chance; the double-blind method prevents both participants and researchers from knowing which treatment is being taken. Seventy-six people with type 2 diabetes and non-alcoholic fatty liver disease—that is, fat accumulation in the liver not attributed to alcohol consumption—received 1,000 mg of ginger twice a day or a placebo for three months. Body circumferences, blood pressure, blood tests, and FibroScan, a non-invasive test that estimates liver fat and stiffness, were measured. In both groups, body mass index, circumferences, and transaminases—enzymes that can increase when the liver is under stress—decreased. In the ginger group, insulin and HOMA-IR, an estimated index of insulin resistance, decreased, and HDL cholesterol increased. Systolic and diastolic blood pressure also improved. However, no significant changes emerged in inflammatory markers or FibroScan indices related to steatosis and controlled attenuation. The work therefore suggests a possible short-term metabolic signal, not proof that ginger reduces liver fat or alters the course of the disease.